Angela Rivers, M.D., Ph.D.

Division

Hematology and Oncology

Academic Title

Assistant Professor

Contact Information

352-273-9120 (phone)
352-392-8725 (fax)
arivers@peds.ufl.edu

Office

UF Pediatrics, Division of Hematology/Oncology
PO Box 100296
Gainesville, FL 32610-0296

Training

• Bachelor of Arts, Simon’s Rock of Bard College, June 1993
• Ph.D. Meharry Medical College, Dec 1998
• M.D. Stanford Univeristy, June 2002
• Residency. University of South Florida Florida, June 2006
• Fellowship. University of Florida , June 2009
• Board Certification, Medicine, 2006
• Board Certification, Pediatric, 2007

Clinical Interests

• Sickle Cell Disease
• Hemophillia
• Thrombosis

Research Interests

• Adeno associated virus as a vector for gene therapy of hematopoietic stem cells

About

“Dr. Angela” research focuses on double stranded, self-complementary, Adeno-Associated virus (scAAV) to deliver an antisickling globin to hematopoietic stem cells as curative therapy for Sickle Cell Disease. This work is funded by K01 from NIHLBI. She is a founding member of CASIRE(Consortium for the advancement of Sickle Cell Research), a clinical research group.

Key Publications

1. Rivers AE and Arun Srivastava. A Guide to Human Gene Therapy: Chapter 12:Gene therapy of Hemoglobinapathies. World press, 2010
2. Giridharar Jayandharan, Li Zhong, Brandon Sack, Angela E. Rivers, Mengxin Li, Baozheng Li, Roland Herzog and Arun Srivastava. Optimized AAV-protein phosphatase 5 helper-viruses for efficient transduction by single-stranded AAV vectors: Therapeutic expression of Factor IX at reduced vector doses. Hum Gene Ther. 2010 Mar;21(3):271-83
3. Rivers AE and Slayton WB. Congenital Cytopenia and Bone Marrow Failure Syndromes. Semin Perinatol. 2009 Feb;33(1):20-8.
4. Maina N, Zhong L, Li X, Zhao W, Han Z, Bischof D, Aslandi G, Zolothukin S, Weigel-Van Aken KA, Rivers AE, Slayton WB, Yoder MC, Srivastava A. Optimization of Recombinant Adeno-Associated Virus Vectors for Human ß-Globin Gene Transfer and Transgene Expression. Human Gene Therapy.2008 Apr;19(4):365-75
5. Slayton WB, Patel M, Sola-Visner M, Harris N, Rivers AE, Montgomery RR, Friedman KD. Type 2B von Willebrand disease associated with the release of platelet agglutinates from megakaryocytes in the bone marrow. Journal of Pediatric Hematology/Oncology, 2008 sep;30(9): 708-11.
6. Maina N, Zhong L, Li X, Zhao W, Han Z, Bischof D, Aslandi G, Zolothukin S, Weigel-Van Aken KA, Rivers AE, Slayton WB, Yoder MC, Srivastava A. Optimization of Recombinant Adeno-Associated Virus Vectors for Human ß-Globin Gene Transfer and Transgene Expression. Human Gene Therapy.2008 Apr;19(4):365-75